Research Journal of Pharmacy and Technology

Pantoea agglomerans bacterium based on Enterobacteriaceae acts as an opportunistic pathogen in patients with immune compromised, causing sepsis, wound infections and urinary tract infections. Anoverall of80Hemodialysis catheters swaps was collected from patients attended to Hemodialysis unit-Baqubah teaching hospitalin Diyala province-IRAQ. P. agglomerans was diagnosed by using selective media and many biochemical tests then VITEK system used to confirm these isolates. Antibiotics susceptibility test was performed using Kerby-Bauermethod. Minimum inhibitory concentration for Zink O and Silver O nanoparticles was detected by using standard agar dilution method. More than48isolates, 10 (20.8%) belonging to P. agglomerans, were uniformly susceptible to Augmentin, Gentamycin, Chloramphenicol. All isolates were resisted to Amikacin and cephalexin. Most of these isolates showed multidrug-resistant against Antibiotics targeted. The MIC ranging value for ZnONPs were between (652–12500 μg/ml) while for AG NPs were(652–5000 μg/ml)