Research Journal of Pharmacy and Technology

The study investigated the effect of lead at concentrations of 0.5mgL-1, 1.0mgL-1, 1.5mgL-1 on the hematocrit index, hemoglobin content, number of red blood cells, white blood cells in Oreochromis sp. Experimental results showed that the concentration of lead is inversely proportional to hematocrit, hemoglobin content, the number of red blood cells of Oreochromis sp. and is directly proportional to the number of white blood cells. When lead exposure in another groups at the investigated concentrations, the hematocrit index was reduced to 13.67%, 28.66% and 33.67%, respectively compared to the control; hemoglobin content decreased by 24.69%, 29.46%, 30.68% compared to control; Red blood cells decreased by 17.25%, 21.18% and 26.67%, respectively, compared to controls; increased white blood cell count by 9.81%, 24.61%, 34.48% compared to control.