Department of Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, 576 104, Udupi, Karnataka, India
In the present day scenario, where novel drug delivery system and controlled drug delivery systems have been developed over the conventional oral solid dosage forms, pellets emerged as a versatile delivery system. Pelletization is a technique to obtain pellets or spherical particles having a dimensions between 0.5–1.5 mm. These multiparticulate systems are either compressed into tablets or filled into capsules.
The following review provides a brief outline on pelletization. In this review, we have discussed on various parameters affecting pelletization, different techniques of pelletization and assessment of pellets.
It is expected that the pellatizaiton is an effective and efficient approach which can help in improvement of absorption, bioavailability, stability, etc. Pellets can offer therapeutic advantages with effordable cost. Several studies are performed to address the limitations of numerous drugs.
Multiparticulate systems, pellets, pelletization, oral solid dosage, controlled drug delivery
