1Faculty of Bio-economy and Health Sciences, Geomatika University College, Kuala Lumpur, Malaysia-54200
2Department of Pharmacology, Faculty of Medicine, MAHSA University, Malaysia-42610
3Faculty of Pharmaceutical Sciences, UCSI University, Kuala Lumpur, Malaysia-56000
4Faculty of Medicine and Health Sciences, UCSI University, Kuala Lumpur, Malaysia-56000
*Corresponding Author E-mail: samiveni@gmail.com
Online published on 24 December, 2019.
To investigate the antioxidant, antidiabetic, and antihyperlipidemic activities of Dolichandrone atrovirens in albino wistar rats.
Bark and leaf part of Dolichandrone atrovirens were extracted with water and methanol. Swiss albino wistar rats were used to evaluate the in vivo effects of streptozotocin induced body weight loss, oxidative stress, hyperglycemia and hyperlipidemia.
Data were analysed by One -way ANOVA, followed by Turkey –Kramer Multiple Comparison Test.
Dolichandrone atrovirens extract treated animals demonstrated significant increase in body weight, decreased blood glucose levels, glycosylated haemoglobin and changes in other biochemical parameters levels when compared to diabetic control rats.
Dolichandrone atrovirens, streptozotocin, in vivo activity, antidiabetic
