Research Journal of Pharmacy and Technology

SCOPUS
  • Year: 2019
  • Volume: 12
  • Issue: 8

Evaluation of the Antimicrobial activity of Cumin oil mediated silver nanoparticles on Oral microbes

1Under Graduate Student, Dept.of Pharmacology, Saveetha Dental College, Saveetha Institute of Medical and Technical Science (SIMATS), Saveetha University, Chennai, India

2Associate Professor, Department of Pharmacology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences (SIMATS), Chennai, Tamil Nadu, India

Abstract

The aim of the study was to synthesise cumin oil mediated silver nanoparticles and to evaluate its effect on oral microbes.

Silver nanoparticles have been assessed for their catalytic, various optical, magnetic andantibacterial properties. It has a large application in the various fields such as photography, biosensor, biomolecular detection and in cosmetics.

The silver nanoparticles were prepared initially using cumin oil and confirmed both visually as well as spectrophotometrically. The antimicrobial activity of the cumin oil mediated silver nanoparticles were then evaluated by agar well diffusion method and the zone of inhibition was recorded against oral pathogens such as Streptococcus mutans, Staphylococcus aureus and E.fecalis.

The cumin oil mediated silver nanoparticles showed dose dependent antimicrobial activity with very good zone of inhibition against the tested oral pathogens.

This study prove that cumin oil mediated silver nanoparticles can be used for the control of infections caused byStreptococcus mutans, Staphylococcus aureus and E.fecalis.

Keywords

Silver nanoparticles, anti microbial activity, cumin oil