Research Journal of Pharmacy and Technology

Agaricus bisporus is generally available in the grasslands of Europe and North America. The most popularity as edible mushroom species in the world, portobello mushroom, is due to its high level of nutrients. Most commonly, dietary fiber (chitin), essential, semi-essential amino acids, unsaturated fatty acids including linoleic and linolenic acids, easily digestible proteins, sterols, phenolic and indole compounds, and vitamins − especially provitamin D2 and B1, B2, B6, B7, and C are available in A. bisporus. The present study was an attempt to establish the possible phytochemical and biological activities (anti-inflammatory, analgesic, antipyretic, antioxidant and antimicrobial) of alcoholic (methanol) and aqueous extract of A. bisporus. First three activities were evaluated using Swiss albino mice (In-vivo) and the remaining two activities were In-vitro study. Both the extracts at higher concentration showed significant Anti-inflammatory, analgesic, antipyretic and antioxidant activities. In addition, methanolic extract also displayed antimicrobial activity.