Research Journal of Pharmacy and Technology

SCOPUS
  • Year: 2019
  • Volume: 12
  • Issue: 9

Screening of Complement Stimulating Activity of Lindernia madayiparense Extracts

1Department of Pharmaceutical Chemistry, Swamy Vivekanandha College of Pharmacy, Nammakkal-637205, Tamil Nadu, India

2Department of Pharmacy, Faculty of Engineering and Technology, Annamalai University, Annamalainagar-608002, Tamil Nadu, India

Online published on 24 December, 2019.

Abstract

This study evaluates the influence of different extracts of newly identified Lindernia madayiparense from Linderniaceae on complement system. The similar species under this family are used in China and India to prevent and cure diverse ailments and to rejuvenate the immune system without any marketing standards. Various extracts of plant were evaluated through complement mediated hemolytic assay. Two plant extracts shows complement modulating property against alternative pathway of complement system, i.e. ethanol extract and decocted extract. These fractions showed significant complement stimulating activity compared to positive control used.

Keywords

Linderniaceae, Lindernia madayiparense, complement, alternative pathway, immunomodulatory, Hemolytic assay