Recent Approaches in Transdermal Drug Delivery System

Transdermal drug delivery has been applied as a safe and efficient delivery system since 1981. TDDS recently accessible to dominate the problems of drug delivery over the oral route. Transdermal film is a therapeutic adhesive film which is used on the skin to deliver a particular amount of drug over the skin as well as systemic circulation. Development of an effective TDDS is dependent to physicochemical properties of drug, excipients and manufacturing possesses. For achieving systemic effect, many new carriers have been established such as Liposomes, Niosomes, Transfersomes, Cubosome and Ethosomes, an enormous request for pharmaceutical and cosmeceutical industry, it has capability to controlled the release of active ingredient, enhance consistency and bioavailability. In this review, we have summarized many physicochemical approaches for transdermal drug delivery system, containing classification of TDDS, enhancing the permeability of drug over the skin, marketed formulation and application of transdermal drug delivery system.