Research Journal of Pharmacy and Technology

SCOPUS
  • Year: 2020
  • Volume: 13
  • Issue: 1

Anti-Oxidants used for the Treatment of Alzheimer Disease

Department of Pharmaceutics, School of Pharmaceutical Sciences, Vels Institute of Science Technology & Advance Studies University, Chennai-600117, India

Abstract

Alzheimer's disease is a neurological syndrome that showed in cognitive and behavioral impairment. An initial stage of diagnosis and treatment of this brain disease is the main challenge, which is mainly stopped by the lack of validated process. The brain is vulnerable to oxidative stress when we compared with other organs and utilization of neurons components such as lipids, proteins, and nucleic acids, it can be oxygenized in Alzheimer Disease regarded to mitochondrial dysfunction, improved metal levels, inflammation, and β-amyloid (Aβ) peptides. Often several theories cautioned to AD etiology, reactive oxygen species (ROS) technology is noted as a not unusual element. They try to lessen the pathology linked with reactive oxygen species (ROS) beneath antioxidants as a result it provides new self-assurance to patients tormented by this devastating disorder.

Keywords

Alzheimer disease, oxidative stress, antioxidant, and ROS