Research Journal of Pharmacy and Technology

SCOPUS
  • Year: 2020
  • Volume: 13
  • Issue: 2

Anti-anxiety effect of Aerva lanata (L.) using mice model

Department of Pharmacology, NGSM Institute of Pharmaceutical Sciences, A constituent college of Nitte Deemed-to-be University, Paneer, Derlakette, Mangalore-575018

1College of Pharmacy, Graphic Era Hill University, Bhimtal Campus Uttarakhand-263156

Abstract

The present research aims to evaluate the anti-anxiety activity of ethanolic extract of Aerva lanata (L.) (Amaranthaceae). The study was performed using Albino mice of either sex. Ethanolic extract of Aerva lanata was administered at a doses of 100mg/kg and 400mg/kg body weight (p.o). The elevated plus maze (EPM) and Light dark transition (LDT) tests were used to determine the anti-anxiety activity. The results of the present study demonstrated that the mice treated with the Aerva lanata (L.) extract produced significant anxiolytic effect in both the animal models of anxiety, when compared to the control group.

Keywords

Anti-anxiety, Elevated plus maze, Light dark transition, Aerva lanata.