Research Journal of Pharmacy and Technology

SCOPUS
  • Year: 2020
  • Volume: 13
  • Issue: 6

Synthesis and Antibacterial activity of some newer Benzimidazole derivatives

Department of Pharmaceutical Chemistry, Rajiv Academy for Pharmacy, N.H. #2, Mathura Delhi Road, P.O. chhatikara, Mathura, Uttar Pradesh (India) 281001

Abstract

A series of some newer benzimidazole derivatives were synthesized and evaluated for their anti-bacterial activity. Some of new benzimidazole derivatives are derived from the parent compound. The result shows all the compounds have low micromoler minimal inhibitory concentration (MIC) gives a good antibacterial activity against Gram-positive or Gram-negative bacteria. Benzimidazole is the heterocyclic compound formed from benzene ring and five-member ring containing nitrogen and its derivatives are wide interest because of their diverse biological activity and clinical applications.

Keywords

Benzimidazole, newer derivatives, antibacterial activity, spectral analysis