Research Journal of Pharmacy and Technology
SCOPUS
  • Year: 2020
  • Volume: 13
  • Issue: 9

Formulation and evaluation of fast dissolving tablet of clopidogrel

1Department of Pharmaceutics, School of Pharmaceutical Sciences, Vels Institute of Science Technology and Advanced Studies, Pallavaram, Chennai, 600117

2Department of Chemistry, School of Pharmacy, Sri Balaji Vidyapeeth Deemed to be University, Puducherry, India

*Corresponding Author E-mail: pgmahesh83@gmail.com

Online published on 16 September, 2020.

Abstract

Clopidogrel is used to treat heart attack and strokes in persons with heart disease (recent heart attack). It helps keep blood flowing smoothly in your body.

Difficulty in swallowing (dysphasia) is a common problem of all age groups, especially the elderly and pediatrics, because of physiological changes associated with these groups.

In the present work it has been observed from all formulations of Precompression and post compression studies were given within the limit of values. The in vitro dissolution data, F1 (combination of different superdisintegrants) formulation was found that the drug release is best and the cumulative % of drug release was 90.88% respectively, when compared to other formulation.

Keywords

Clopidogrel, Dysphasia, Superdisintegrants, Cumulative