Breast cancer is the second most common cancer in females. VEGF-C overexpression has been reported in breast cancer patients, and correlates with metastasis and poor prognosis. Objective: Determination the serum VEGF-C concentration in breast cancer patients, and its change after treatment.
This is a prospective, cross sectional study, include 65 women (30 with breast cancer, 35 healthy) met the study criteria. the serum VEGF-C values were measured at the beginning and after finishing the treatment.
There is no differences in age between two groups, The mean of serum VEGF-C values was higher in breast cancer patients (1122.74±853.97 U/L vs 334.55±522.6 U/L; P<0.00),. Serum VEGF-C level was significantly higher in breast cancer patients before the treatment compared with after treatment (P <0.01).
Serum VEGF-C value has a good correlation with breast cancer.
Breast Cancer, VEGF-C
