Research Journal of Pharmacy and Technology
SCOPUS
  • Year: 2020
  • Volume: 13
  • Issue: 9

Phytochemical screening and antioxidant activity of Hypsizygus ulmarius (Bull.)

1Research Scholar in Microbiology, Department of Botany, Maulana Azad Collage of Arts, Science and Commerce, Dr. Rafiq Zakaria Campus, Rauza Bagh, Aurangabad, Maharashtra, India

2Assistant Professor of Botany, Department of Botany, Maulana Azad Collage of Arts, Science and Commerce, Dr. Rafiq Zakaria Campus, Rauza Bagh, Aurangabad, Maharashtra, India

3Associate Professor of Microbiology, Department of Microbiology, Badrinarayan Barwale Mahavidyalaya College, Jalna, India

*Corresponding Author E-mail: lenaalfaqeeh8@gmail.com

Online published on 16 September, 2020.

Abstract

Mushrooms have been used by ancient people due to their nutritional and medicinal value. The present study aimed to evaluate phytochemical compounds and antioxidant activity of Hypsizygus ulmarius (Bull.) methanolic extract and its fractionation. Phytochemical analysis showed the presence of alkaloids, tannins and phenolic compounds, flavonoids, anthraquinone, saponin, coumarin and steroids. Petroleum ether fraction contain tannins and phenolic compounds which are absent in ethyl acetate fraction. Antioxidant activity using DPPH assay showed that IC50 of methanolic extract, petroleum ether and ethyl acetate fractions were 8.4μg/ml, 7.44 μg/ml and 6.77μg/ml, respectively. Hypsizygus ulmarius (Bull.) may be consider as a good source for phytochemicals and antioxidant which can be used in medical and pharmaceutical research. Furthermore, study carried out for the antimicrobial and anticancer activity of methanolic extract and its fractionation is under process.

Keywords

Hypsizygus ulmarius, Methanolic extract, Petroleum ether and ethyl acetate fractions, Phytochemicals, DPPH radical scavenging assay