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*Corresponding Author E-mail: rschandan@jssuni.edu.in
The measurement of teneligliptin in a drug pure in compliance with the ICH Guidelines, an easy and extraction free UV spectrophotometric method, was developed and validated. At 246nm and linearity of concentration of 10–50μg/ml, the drug shows strong absorption. The process for relaying the drug reaction to MeOH was calculated by its absorption maximum (λmax) 246nm in order to achieve a colorless solution. In the 10–50μg/ml concentration range, the rule on beer complied. The calibration chart was found to be linear, and the coefficient of correlation (r2) was found to be 0.9952%. The experimental value LOD and LOQ parameters for the proposed procedure are measured, respectively, like 2.25 and 6.83μg/mL. Teneligliptin recovery was reported as 101.58%. To maximize the reaction condition, all of the parameters were analyzed.
Teneligliptin, MeOH, Validation, ICH guidelines