The effect of antihypertensive herb formula of Indonesian traditional medicines against serum uric acid levels in mild Hypertensive patients

The objective of the study was to determine the effect of herb formula consisting of Syzygium polianthum leaves, Centella asiatica leaves, Imperata cylindrica roots, Myristica fragrans seeds, Curcuma xanthorizza rhizomes, Curcuma longa rhizomes and Phyllanthus niruri herbson serum uric acid levels of patients with mild hypertension. This research method was a quasi-experimental study with pre-post control design, noncomparative, conducted at clinical of saintification of jamu Hortus Medicus over 8 weeks. As much as 60 volunteers-fulfilling the inclusion and exclusion criteria were recruited as subjects. Serum uric acid level, renal and liver function were calculated at baseline, middle and end of study (at the end 8 weeks). There was a statistically significant difference between mean serum uric acid level at baseline and the end of treatment on mild hypertensive patients with hyperuricemic, which had a p-value < 0.05 (p = 0.023 (CI 95% 0.15–1.64)). Nevertheless. the number of subjects with hyperuricemia increased from 21.6% to 23.3%. at day 56. This study concludes that the antihypertensive formula is more favorable in lowering serum uric acid levels in mild hypertensive patients which had hyperuricemia.