RESEARCH JOURNAL OF PHARMACY AND TECHNOLOGY
SCOPUS
  • Year: 2021
  • Volume: 14
  • Issue: 1

Evaluation of Antibacterial and Antioxidant activities of Tribulus terrestris L. Fruits

1Department of Zoology, Maulana Azad Collage, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad, India.

2Department of Zoology, Maulana Azad Collage, Dr. Rafiq Zakaria Campus, Aurangabad, India.

*Corresponding Author E-mail: latifaabdulqawi@gmail.com

Online published on 22 April, 2021.

Abstract

The present study comprises screening some phytochemical compounds, antimicrobial activity and antioxidant activity in methanolic and aqueous extracts of Tribulus terrestris L fruits. The phytochemical analysis revealed the presence of alkaloids, Tannins, Glycosides, Flavonoids, Saponins, and Phenols. A well-diffusion method determined the antibacterial effect of T. terrestris extracts against both Gram-positive (Staphylococcus auras and Methicillin-resistant Staphylococcus aureus ATCC43300 (MRSA), and Gram-negative bacteria Pseudomonas aeruginosa, Proteus mirabilis, Klebsiella pneumoniae, and Escherichia coli ATCC25922. The methanolic extract was the most active extract against tested bacteria with a minimal inhibitory concentration (MIC) value of 6.25mg/ml. An antioxidant activity using DPPH assay showed that IC50 of methanolic and aqueous extracts were 3.94μg/ml and 22.45μg/ml, respectively).

Keywords

Tribulus terrestris, Phytochemical, Antibacterial, Antioxidant