RESEARCH JOURNAL OF PHARMACY AND TECHNOLOGY
SCOPUS
  • Year: 2021
  • Volume: 14
  • Issue: 1

A review on the total synthesis of (−)-Swainsonine natural product (2005–2020)

Department of Chemistry, College of Science, University of Baghdad, Al-Jadriya Campus, Baghdad10071, Iraq

*Corresponding Author E-mail: rafid.s@sc.uobaghdad.edu.iq

Online published on 22 April, 2021.

Abstract

This review aims to cover the literature published methodologies of the total synthesis of the (−)-swainsonine alkaloid natural product that has been reported between the years 2005 and 2020. (−)-Swainsonine has been widely studied for many important biological activities and scientifically reported to possess such as anticancer, antimetastatic, antitumor, antiviral and anti-HIV.

Keywords

(−)-Swainsonine, Indolizidine alkaloids, Anticancer activities