Research Journal of Pharmacy and Technology
SCOPUS
  • Year: 2021
  • Volume: 14
  • Issue: 10

Hypocholesterolemic Operating Parameters of Novel Probiotics In vitro

Botany and Microbiology Dept., Faculty of Science (Boys), Al-Azhar University, Cairo, Egypt

*Corresponding Author E-mail: amrelwaseif@azhar.edu.eg

**hussein.sayed.2016@gmail.com

***ewais_e@yahoo.com

Online Published on 22 February, 2022.

Abstract

The Hypocholesterolemic is an effective and friendly process for the removal of cholesterol and an important aspect of human health. Removal of cholesterol by probiotic bacteria was investigated in this study. The potential probiotic bacterium was preliminarily identified as Lactobacillus casei. In addition, the various operating parameters like cholesterol concentration, incubation time, bile salts concentration, probiotic dose and initial pH was studied. The optimum parameters for most probiotics studied are cholesterol concentration is 100 μg/ml, incubation time is 48 h, bile salts concentration is 0.5%, probiotic dose is 200μl and initial pH is 6. The maximum percentage removal of cholesterol using Lactobacillus casei is 93.6. The probiotics bacteria are favorable for Hypocholesterolemic.

Keywords

Cholesterol, Probiotic, Lactobacillus, Hypocholesterolemic activity