Evaluation of Phytochemical constituents and Antioxidant potential of hydro-alcoholic extract of seeds of Petroselinum crispum

Free radicals are generated inside the body during various physiological processes and these free radicals are scavenged by the anti-oxidants present in the body and hence a balance is maintained between these free radicals and anti-oxidants. An imbalance between these free radicals and anti-oxidants lead to a state known as oxidative stress which is one of the main culprits of several diseases. Many medicinal plants are a rich source of anti-oxidants and have been used since time immemorial to combat these diseases by providing various anti-oxidants. The present study was proposed to investigate the phytochemical constituents and anti-oxidant potential of hydro-alcoholic extract of seeds Petroselinum crispum. Phytochemical analysis was performed using different methods and anti-oxidant activity was evaluated by measuring total phenolic content, reducing power assay, hydrogen peroxide (H2O2) scavenging activity, DPPH radical-scavenging activity, superoxide radical-scavenging activity, phosphomolybdenum free radical scavenging activity and nitric oxide radical scavenging activity. The results showed that the hydro-alcoholic extract of seeds P. crispumare a rich source of flavanoids, triterpenoids, phenols, tannins, saponins and amino acids and possess a significant quantity of flavonoids, terpenoids, saponins. It was also revealed that hydro-alcoholic extract of seeds P. crispumpossess a significant anti-oxidant activity as evaluated by using different anti-oxidant assays.