Research Journal of Pharmacy and Technology
SCOPUS
  • Year: 2021
  • Volume: 14
  • Issue: 10

Liquisolid Compacts Technique of Poor Water Soluble Drugs: An Overview

1Department of Pharmacy Practice, Vels University, Pallavaram, Chennai

2PhD Research Scholar, Vels University, Pallavaram, Chennai

*Corresponding Author E-mail: mohan.dhere@rediffmail.com

Online Published on 22 February, 2022.

Abstract

Liquisolid technique is new and promising method that can use to enhance the dissolution rate of poorly water soluble drugs. Liquisolid compact technique is based upon the dissolving the drug in a suitable non-volatile solvent by using carrier and coating material for the conversion of acceptable flowing and compressible powders. By applying the mathematical models the carrier and coating materials optimized. In this case the drug is almost solubilised in the solvent or molecularly dispersed state which contributes the enhanced drug dissolution.

Keywords

Liquisolid technique, Poorly water soluble drugs, Dissolution rate enhancement, Oral bioavailability