1Department of Chemistry, Moscow Institute of Physics and Technology, Dolgoprudny, Moscow Region, Russian Federation
2Department of Chemistry and Technology of Organic Synthesis, D. Mendeleev University of Chemical Technology of Russia, Moscow, Russian Federation
3Department of Pharmacology, Perm State Pharmaceutical Academy, Perm, Russian Federation
*Corresponding Author E-mail: talismanovpharm@mail.ru
Online Published on 02 March, 2022.
In vitro tests of substituted 1, 3-dioxolanes, based on cyclic ketones and substituted with 1H-1, 2, 4-triazole and 1H-imidazole showed a fungicidal activity lower than the activity of the triadimefon, and spiroxamine. Studied compounds in the entire concentration range: from 0.001 to 10 mg/L showed noticeable retardant properties. The target compounds were derived by cyclization of substituted cyclohexanones with epichlorohydrin followed by alkylation of the derived 2-chloromethyl-1, 3-dioxolanes of sodium salts of imidazole or 1, 2, 4-triazole.
Alkylation, 1, 3-dioxolane, Growth-regulating activity, Imidazole, Fungicidal activity, Ketalization, Ketals, 1, 2, 4-triazole
