1Department of Chemistry, Banasthali University, Banasthali, Rajasthan, India-304022
2Department of Chemistry, SMS Research Center (ADSIR Approved Facility) SMS Pharmaceuticals Ltd; Hyderabad, Telangana, India500043
*Corresponding Author E-mail: shrikanthavale@yahoo.com, svr.org@gmail.com
Online Published on 02 March, 2022.
A new derivative synthesis of Substituted-N-((1, 3-diphenyl-1h-pyrazol-4-yl) methyl) benzenamine has attempted by using commonly available key starting materials Acetophenone (1) and substituted phenyl hydrazine in presence of sulfuric acid catalyst and alcohol solvent to afford potential antiviral active analogues. The synthesis proceeds through Vilsmeier-Haack reaction followed by reductive amination by using sodium borohydride.
(1, 3-diphenyl-1H-pyrazol-4-yl) methyl) benzenamine, Vilsmeier-Haack reaction, Reductive amination with sodium borohydride