Viscometric study of metformin complexes with some transition metal ions at different temperatures

The measurement of densities, specific viscosities of metformin drugs complexes with some transition metal ions at different concentration in the range (1 x10⁻² M to 6 x10⁻⁴ M) in 70% (DMSO + water) solvent at 303K are reported. The experimental data shows, the effect of concentration of solute on viscosity in DMSO-water mixtures which gives idea about the molecular interactions present in different solutions. Appreciable molecular interactions were observed between the metal complexes of metformin and binary mixture. The thermodynamic properties such as free energy change (ΔG), enthalpy change (ΔH) and entropy change (ΔS) of metal complexes of metformin drugs were analyzed in 70% (DMSO + water) mixture at different temperature such as 308 K, 313 K and 318 K. The experimental data gives the idea about effect of temperature on the molecular interaction and structural changes in solute.