Evaluation of Anti-inflammatory activity of ethanolic extract of Populus deltoides

The ethanolic leaves extract of P.deltoides was tested for the presence of various phytoconstituents using standard procedure and study was designed to evaluate the anti-inflammatory activity in rodents. Anti-Inflammatory activity of leaves extract of P.deltoides (250 and 500mg/kg) was studied in carragenin induced paw edema and cotton pellet granuloma in rat. The ethanolic leaves extract of plant revealed the presence of variety of chemical constituents like terpenoids, alkaloids, flavonoids, tannins, saponins, amino acids and glycosides. Leaves extract of P.deltoides significantly showed anti-Inflammatory activity in carrageenin induced paw edema by reducing paw volume in rats. From our study we concluded that leaves extract of P.deltoides has potential to anti-inflammatory and suggests that it can be used in the management of inflammation, thus providing a scientific basis for its traditional use.