Department of Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal-576104, Karnataka, India
Scientific and technological advances have been made in recent years in researching and developing the oral drug delivery mechanism. The explanations for this success gained by the oral route can be attributed to the convenience of administration. One of the most common oral products is chewing gum. Chewing gums are systems for the oral delivery of drugs. Medicated gums cannot be swallowed, as compared to chewable pills and can be removed without resorting to invasive means from the application site and the Medicated Chewing Gum (MCG) preparation is solid, one-dose product. It is discreet and easy way to administer without water that promotes higher patient compliance. This comprises of single or many active components which are chewed and made available for absorption by the buccal mucosa for local mouth disease like dental cavities treatment or for systemic supply. Here in this review, various formulation aspects and manufacturing processes of MCG are explored along with their advantages and drawbacks of MCG. MCG is one of the newest tools with a future potential in pharmaceuticals, OTC medicinal products and nutraceuticals.
Medicated Chewing Gum, Oral Mucosal Delivery of Medications, Dental Cavities
