Nanosponges: An innovative approach for targeted drug delivery system

The nanosponge is the novel and emerging technology which plays a vital role in targeting drug delivery in the controlled manner. The nanosponges are tiny sponges having size of about a virus and it can easily penetrate through the skin. The tiny sponges circulate around the body until they reach to the specific target site and stick on the surface and start to release the drug in controlled manner. It releases the drug at specific site instead of circulating overall body it is more effective for targeted drug delivery system as they enhance solubility, bioavailability and reduces side effects. Nanosponges prevent drug and protein degradation. Both hydrophilic and lipophilic drugs are incorporated in Nanosponge. In this review mechanism, method of preparation, evaluation, stabilization and applications of nanosponges are discussed.