RESEARCH JOURNAL OF PHARMACY AND TECHNOLOGY
SCOPUS
  • Year: 2021
  • Volume: 14
  • Issue: 3

Vinorelbine: A potential breakthrough in cancer therapy

1Institute of Pharmaceutical Research, GLA University, Mathura,, Uttar Pradesh, 281406, India

2Jai Institute of Pharmaceutical Sciences and Research, Vism Campus, Gwalior, Madhya Pradesh, 474001, India

*Corresponding Author E-mail: Varshabandil98765@gmail.com

Online published on 30 April, 2021.

Abstract

Vinorelbine is a semi synthetic vinca organic compound that has been exposed dynamic in numerous tumor types and is right now enrolled for the cure of advanced breast cancer (ABC) and non-small cell lung cancer (NSCLC). Evaluation of its pharmacokinetic and toxic outline and give understanding into its future as a NSCLC and ABC remedial. Its marketed formulation has been accounted for to have serious aspect effects, like venous irritation and phlebitis proximal to the site of infusions, likewise restricted rashes and urticaria. Our long run aim in synthesizing a novel nanomicellar vinorelbine formulation is to decrease or perhaps eliminate these adverse effect and increment medicate action by formulating the medication in a lipid-based framework as a nanomedicine focused to the location of activity.

Keywords

Vinorelbine, Advanced Breast Cancer, Non-Small Cell Lung Cancer, Sterically Stabilized Micelles