Evaluation of antioxidant and hepatoprotective activity of biomass and crude astaxanthin extract of green alga Haematococcus pluvialis

In the present investigation, effect of biomass, crude astaxanthin of Haematococcus pluvialis on the different hepatic and antioxidant enzymes against toxin, carbon tetrachloride (CCl₄) induced toxicity on male Albino Wistar rat, weighing 200-220g which were compared with the commercially available astaxanthin and ascorbic acid all are mixed in liquid paraffin and feeding (orally) of 100μg/kg b.w of commercially available astaxanthin, biomass, crude extract, and ascorbic acid was started 2 weeks before to CCl₄ treatment. The animals were sacrificed after 24 h of CCl₄ treatment, collected samples, for the evaluation of hepatic and antioxidant enzymes Biomass (100μg/kg b.w) treated groups restored maximum damage induced by the CCl₄, when results were compared with the toxin treated group. These results indicate that H. pluvialis biomass and crude extract showed umpteen hepatoprotective and antioxidant activity and thus can be used for various food formulations for human welfare.