1Department of Pharmacy Practice, College of Clinical Pharmacy, King Faisal University, Al-Ahsa, Saudi Arabia
2Department of Pharmaceutics, Vidya Siri College of Pharmacy, Off Sarjapura Road, Bangalore-560 035, Karnataka, India
3Department of Biotechnology and Biomedicine, Faculty of Biology, Environmental Sciences
4Chemistry, University of Alcalá, Madrid-Barcelona Road, Km. 33.6, Edificio De Ciencias Calle 24 28805, Alcalá de Henares, Madrid, Spain.
5Department of Pharmacognosy, Government College of Pharmacy, Bengaluru, India.
Online published on 3 June, 2021.
Viruses are change-prone entities often used as models to study evolutionary mechanisms. SARS-CoV-2 has shown a rapid adaptation to its new host, the human. In addition, it is now widely considered to be the most infectious RNA viral particle in humans, due to both efficiency in transmission mechanisms and exposure. Despite the large number of published articles that shed light on this virus, there is no analysis of the quantitative change in the ultrastructure of SARSCoV-2, although it is a useful tool for understanding the evolutionary pattern. To avoid the emergence of at least three completely different viruses, it should appear that an effective vaccine contains the diversification of the SARS-CoV-2 evolutionary tree. In addition, a greater understanding of the physicochemical characteristics acquired by each of the viral haplotypes is required. In the meantime, the following discussion is offered to update developments in this research topic and to relate them so we can answer questions that, until now, have not been addressed.
SARS-CoV-2, Coronavirus, Epidemic, SsRNA
