Research Journal of Pharmacy and Technology

SCOPUS
  • Year: 2021
  • Volume: 14
  • Issue: 5

An overview on niosomes: As an auspesious drug delivery system on the bases of application

Assistant Professor, Faculty of Pharmacy, IFTM University, Moradabad (U.P.)

*Corresponding Author E-mail: Diksha0712@gmail.com

Online published on 25 August, 2021.

Abstract

In recent years the treatment of infectious diseases and immunisation has undergone a revolutionary shift. Not only a large number of disease-specific biological have been developed, but also contortion has been made to deliver these biological effectively. Conventional dosage forms are unable to deliver the drug in accordance with a predetermined rate and release therapeutically effective amount of drug at the site of action. The vesicular systems of niosomes, having bilayer structure assembled by nonionic surfactants are able to enhance the bioavailability of a drug to a predetermined area for a particular time period. In recent years various comprehensive researchs carried over niosome as a drug carrier and proved to be a promising drug carrier, which has potential to reduce the side effects of drugs and increased therapeutic effectiveness in various diseases. This narrative review describes fundamental aspects of niosomes, formulation methods, methods of characterization, recent advances in niosomal drug delivery.

Keywords

Polyoxyethylene glycol (PEG), Transmission electron microscopy (TEM), Polysorbate 80