Evaluation of cytotoxicity of normal vero and anticancer activity of human breast cancer cell lines by aqueous unripe fruit extract of Solanum torvum
Abstract
In the present study aqueous extract of Solanum torvum unripe fruits was used to evaluate its cytotoxic effect and anticancer activity through in vitro studies by 3-(4, 5 dimethyl thiazole-2-yl)-2, 5-diphenyl tetrazolium bromide-MTT assay) on Normal VERO cell line and MCF-7 (Human breast adenocarcinoma cell line). Aqueous extracts of Solanum torvum unripe fruits was found to be effective in the prevention of cell proliferation by breast adenocarcinoma cell lines at 1000 μg/ml from the results obtained during 24 hours of incubation.
Keywords
Unripe fruits of Solanum torvum, Normal VERO cell line, MCF-7 (Human breast adenocarcinoma cell line), MTT assay
