Research Journal of Pharmacy and Technology
SCOPUS
  • Year: 2021
  • Volume: 14
  • Issue: 7

The use of topical platelet-rich plasma on second degree burn injury: An experimental study

  • Author:
  • Desiree A. Paramita1,*, Deryne A. Paramita2, E S Siregar1, R A Syahputra3
  • Total Page Count: 4
  • Page Number: 3533 to 3536

1Department of Surgery, Faculty of Medicine, Universitas Sumatera Utara, H. Adam Malik General Hospital Medan, Indonesia

2Department of Dermatology and Venereology, Faculty of Medicine, Universitas Sumatera Utara, H. Adam Malik General HospitalMedan, Indonesia

3Department of Pharmacology, Fakultas Farmasi, Universitas Sumatera Utara, Medan, Indonesia

*Corresponding Author E-mail: desireeparamita@gmail.com

Online published on 25 August, 2021.

Abstract

Burn is a tissue injury due to extreme heat, electrical, radiation, corrosive chemical and friction sources. It is one of the major reasons of death and inability and accounts the fourth cause of injuries worldwide. Partial thickness burn damages the epidermis and part of the dermis. Platelet-rich plasma (PRP) has been used in several surgeries and showed a positive result regarding the healing process. In this study, 20 Wistar rats were applied the PRP and 20 others were control Histopathological analysis was done confirming the partial-thickness burn injury. The mean of weight in the control group was 276.2(±14.00) grams compared to 278.7(±11.86) grams in the PRP group, having no statistical difference (p-value 0.609)

Keywords

Platelet-Rich Plasma, Bum