1Department of Analytical and Food Chemistry, Faculty of Pharmacy, Tishreen University, Latakia, Syria
2Department of Pharmacology and Toxicology, Faculty of Pharmacy, Tishreen University, Latakia, Syria
*Corresponding Author E-mail: akramyn99@gmail.com
Online published on 25 August, 2021.
Fruit juices are considered as an important source of phenolic compounds. Black mulberry, pomegranate and orange juices were selected to assess their anti-inflammatory activity. Total phenolic content was determined using Folin-Ciocalteu colorimetric method. The anti-inflammatory activity was evaluated using RBC membrane stabilization method. Ibuprofen was used as a standard drug. Total phenolic content of black mulberry juice, pomegranate juice and orange juice was 3.02 gGAE/l, 1.83 gGAE/l and 0.76 gGAE/l and the percentage inhibition of RBC haemolysis varied between (27.41–43.19%), (24.06–39.06%) and (10.12–22.54%), respectively. Black mulberry juice revealed the highest anti-inflammatory activity among the studied juices. This finding might be attributed to the high phenolic content of this juice compared to others.
Phenolic compounds, Anti-inflammatory, RBC membrane stabilization, Fruit juice