Research Journal of Pharmacy and Technology
SCOPUS
  • Year: 2021
  • Volume: 14
  • Issue: 7

Liver shielding activity of Ficus benghalensis fruit extracts contrary to perchloromethane prompted toxic hepatitis in new zealand albino rats

  • Author:
  • Hindustan Abdul Ahad*, Chinthaginjala Haranath, Naga Jyothi Varam, Tarun Ksheerasagare, Jyothi Vinay Krishna, Siddartha Tharun Teja
  • Total Page Count: 5
  • Page Number: 3739 to 3743

Department of Industrial Pharmacy, Raghavendra Institute of Pharmaceutical Education and Research (RIPER) -Autonomous, Anantapur - 515721, Andhra Pradesh, India

*Corresponding Author E-mail: abdulhindustan@gmail.com

Online published on 25 August, 2021.

Abstract

The main aim of the present investigation was to explore the Liver shielding of Ficus benghalensis fruit extracts alongside perchloromethane persuaded toxic hepatitis in New Zealand albino rats. The ethanolic extract of the fruits of F. benghalensis (Family: Moraceae) was evaluated for Liver shielding in New Zealand Albino rats with liver mutilation persuaded by perchloromethane. F. benghalensis fruit extract unveiled a momentous Liver shielding consequence by dropping the serum concentrations of alanine aminotransferase (ALT), aspartate aminotransferase (AST), total serum bilirubin (TSB) and malondialdehyde equivalent 500 mg/kg (oral). These biochemical explanations were accompanied by a histopathological assessment of liver segments. The liver shielding of F. benghalensis fruit extracts was comparable to that of a known Liver shielding Liv-52.

Keywords

Ficus benghalensis fruits, Liver shielding, New Zealand albino rats