Research Journal of Pharmacy and Technology
SCOPUS
  • Year: 2021
  • Volume: 14
  • Issue: 8

In Vitro evaluation of anti-mitotic activity of green synthesized silver nanoparticles from ethanolic extract of Chromolaena odorata, caesalpinia coriaria (Bark and leaves) using Allium cepa Roots

1PG and Research, Department of Zoology, Guru Nanak College, Chennai600042, Tamil Nadu, India

2Department of Biochemistry/Central Research Lab, Meenakshi Ammal Dental College, Maduravoyal, Chennai600095, Tamil Nadu, India.

3PG and Research, Department of Biochemistry, Dwaraka Doss Goverdhan Doss Vaishnav College, Arumbakkam, Chennai600106, Tamil Nadu, India.

4Department of Research, MAHER (Meenakshi Academy of Higher Education and Research), Chennai, 600078, Tamil Nadu, India

*Corresponding Author E-mail: thivyeshwar@gmail.com

Online published on 1 October, 2021.

Abstract

The scope of the present study was to evaluate the In-vitro biological potential of Green synthesized silver nanoparticles from Chromolaena odorata, Caesalpinia coriaria (Bark) and Caesalpinia coriaria (Leaf). We investigated the effect of green synthesized silver nanoparticles from Chromolaena odorata, Caesalpinia coriaria (Bark) and Caesalpinia coriaria (Leaf) by studying anti-mitotic activity An attempt has been made to evaluate the anti-mitotic activity of silver nanoparticles using Allium cepa roots. The mitotic index of the root tips meristem was calculated and compared with the standard methotrexate. Antimitotic activity results shows the mitotic index was ranged from 30–40%. Green synthesized silver nanoparticles from Chromolaena odorato, Caesalpinia coriaria (Bark) and Caesalpinia coriaria (Leaf) possess significant anti-mitotic activity.

Keywords

Chromolaena odorata, Caesalpinia coriaria (Bark), Caesalpinia coriaria (Leaf), Silver nanoparticles (AgNPs), Methotrexate