Research Journal of Pharmacy and Technology
SCOPUS
  • Year: 2021
  • Volume: 14
  • Issue: 8

In vitro evaluation of the antimicrobial activity of methanolic and aqueous extract of Mucuna pruriens seed

  • Author:
  • Amita Shobha Rao1, K L Shobha1*, Preethi Lavina Concessao2, Gowrish S Rao1, R Sreedhara, K Pai3
  • Total Page Count: 3
  • Page Number: 4212 to 4214

1Dept. of Microbiology, Melaka Manipal Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, India

2Dept. of Physiology, Melaka Manipal Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, India

3Department of Pharmacology, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, Karnataka, India

*Corresponding Author E-mail: shobha.kl@manipal.edu

Online published on 1 October, 2021.

Abstract

The present investigation was to find out efficacy of Mucuna pruriens (M. pruriens) seeds. The antimicrobial activity of methanol and aqueous extract of M. pruriens seeds was determined by well diffusion method with ATCC strains of gram positive and gram negative bacteria clinical strains of multidrug resistant (MDR) Klebsiella pneumoniae, and clinical strains of Candida albicans. It was observed that both the aqueous and the methanol extract of M. pruriens seeds had antibacterial activity against all the ATCC bacterial strains. The MDR strain of Klebsiella pneumoniae was resistant to both aqueous and methanol extract of M. pruriens seed. Antifungal activity against Candida albicans was exhibited by both aqueous and methanol extracts of M. pruriens seed.

Keywords

Mucuna pruriens, Antibacterial, Antifungal, Agar well diffusion test, Methanol extract