Research Journal of Pharmacy and Technology
SCOPUS
  • Year: 2021
  • Volume: 14
  • Issue: 8

Qualitative analysis of ethanolic extract of ginger (Zingiber officinale Rosc) by gas chromatography triple quad time-flight (GC-Q-TOF) technology

1Department of Chemistry, Faculty of Science, Benha University, Benha-Egypt.

2Animal Health Research Institute, Doky, Giza, Egypt

*Corresponding Author E-mail: kareemhagag1010@gmail.com

Online published on 1 October, 2021.

Abstract

This study was carried out to identify of the chemical constituent of ginger (Zingiber officinale Rosc), forty-eight compounds of ethanolic sonicated extract were identified by Gas Chromatography Triple Quad Time-Flight (GC-Q-TOF) analysis. Nineteen of these compounds existed studies on their biological activity, The main components were Zingiberone (4.12%), [10]-Shogaol(2.47%), Methyldiacetoxy-[6]gingerdiol(4.30%), [6]-Gingerdiol3, 5 diacetate(7.77%), [6]-Gingerdiol (2E)-geranial acetal (2.76%), Campesterol (1.52%), Stigmasterol(1.71%), γ-Sitosterol(4.46%), 10S, 11S-Himachala-3(12), 4 diene(3.57%), Cubebol(2.01%), 3α, 9β-Dihydroxy-3, 5α, 8 trimethyltricyclo[6.3.1.0(1, 5)]dodecane(2.24%), 8-Amino-2, 6 dimethoxylepidine(2.13%), 17α-Ethynyl-17β-hydroxy-5β-estran-3-one(2.50%), Tributyl aconitate(2.34%), Ethyl 3, 4-dimethoxy-N-(3-phthalimidopropionyl)-dl phenylalaninate (3.90%), Podocarpa-1, 8, 11, 13-tetraen-3-one, 14-isopropyl-1, 13-dimethoxy (12.51%), 2, 4-Diamino-5, 6-decamrthylenethieno[2, 3-d]pyrimidine(3.65%) and trans-1-(p-(Methylthio)phenyl)-1-dodecen-3-one(6.68%). also minor compounds were present. From this result, it could be concluded that ginger (Zingiber officinale Rosc) contains various bioactive compounds which have various biological activities. Therefore, it is recommended as a plant of therapeutic importance.

Keywords

Analysis, Ethanolic extract, (Zingiber officinale), Bioactive compounds, Gas Chromatography Triple Quad Time-Flight (GC-Q-TOF)