Research Journal of Pharmacy and Technology
SCOPUS
  • Year: 2021
  • Volume: 14
  • Issue: 9

In silico designing of some Benzimidazole derivatives for Anti-fungal activity

  • Author:
  • Amrita Muralikrishnan, Radhika R Nair, Jifitha Banu, Leena K Pappachen
  • Total Page Count: 4
  • Page Number: 4983 to 4986

Department of Pharmaceutical Chemistry and Analysis, Amrita School of Pharmacy, Amrita Vishwa Vidyapeetham, AIMS Health Sciences Campus, Kochi, Kerala, India

*Corresponding Author E-mail: leenakpappachen@aims.amrita.edu

Online Published on 22 February, 2022.

Abstract

Fungus is a kind of living organism and yeast mould and mushrooms are types of fungi. The fungal infections are caused by the fungus. A fungus that invades the tissue can cause a disease that confined to the skin, spread into tissue, bone and organs or affect the whole body. Benzimidazole is a class of heterocyclic aromatic organic compound which posses pharmacological activities including antifungal, antitumor, antiparasitic, analgesic etc. Insilico methods can be used to identify target molecules using bioinformatics tool. The aim of our study was to conduct the insilico drug designing of some benzimidazole derivatives having antifungal activities. In our study the insilico drug design was performed using Biovia discovery studio.

Keywords

Fungal diseases, Ketoconazole, Biovia Discovery studio, Benzimidazole, Molecular docking studies