Department of Chemistry, Jaipur National University, Jaipur-302017, Rajasthan, India
*Corresponding Author E-mail: purnima_nag007@yahoo.com
Online Published on 13 June, 2022.
The interaction of Copper and Nickel chloride with oximes of 2-Acetylfuran, 2-Acetylthiophene and 2-Acetylpyridine in absence of an external base resulted in formation of the complexes of the type [MCl2L2] (A) and [MQ2L2LH2O (A.H2O) {Here M: Cu or Ni; L: HON=C(CH3) Ar; where Ar = C4H3S, C4H3O or C5H4N}. The parent ligands were synthesized by green method using water as a solvent. Complexes were characterized by elemental analysis,1H-NMR, IR spectral studies and these spectra were compared with that of free ligands. Spectral measurements suggest an octahedral or distorted octahedral geometry for all these complexes. The in-vitro Antifungal activity of all these complexes has proven that they are active against Candida albicans even at lower concentrations.
Oximes, Transition Metal Complexes, Copper Complexes, Nickel Complexes, Antifungal Activity
