Research Journal of Pharmacy and Technology
SCOPUS
  • Year: 2022
  • Volume: 15
  • Issue: 10

A potential insect antimicrobial of black soldier fly larvae (Hermetia illucens) against pathogenic bacteria

  • Author:
  • Diyantoro1,2,3,*, Aliyah Siti Sundari1,2, Rizka Oktarianti Ainun Jariah1,2, Dwi Wahyu Indriati1,2, Dwi Wahyu Indriani4
  • Total Page Count: 9
  • Page Number: 4425 to 4433

1Department of Health Science, Faculty of Vocational Studies, Universitas Airlangga, Indonesia

2Antimicrobial Resource Alternative Studies for Emerging and Re-Emerging Infectious Disease, Universitas Airlangga, Indonesia

3Doctoral Program of Medical Science, Faculty of Medicine, Universitas Airlangga, Indonesia

4National Research and Innovation Agency, Indonesia

*Corresponding Author E-mail: diyantoro_dvm@vokasi.unair.ac.id

Online published on 1 March, 2023.

Abstract

Antimicrobial activity of black soldier fly larvae extract against gram-positive and gram-negative pathogenic bacteria has been discovered. Water-soluble extracts have the most potential and effectiveness as antimicrobials, with MIC values ranging from 12.5 to 25 mg/mL for both gram-positive and gram-negative bacteria. BSF larvae also create peptides called defensins and cecropins, which have antibacterial properties. Defensins were the best and most effective peptides in inhibiting bacterial growth, inhibiting both gram-positive and gram-negative bacteria (MIC value = > 29.97 μM), while cecropins were more effective on gram-negative bacteria (MIC value= 0.52 - 2.07 μM) than gram-positive bacteria (MIC value not detected).

Keywords

Insect antimicrobial, BSF Larvae, Pathogenic bacteria