Research Journal of Pharmacy and Technology
SCOPUS
  • Year: 2022
  • Volume: 15
  • Issue: 11

Cytokine storm, immunomodulators and mucormycosis in COVID-19: Bench to bed side

  • Author:
  • Rony T Kondody1, Sudhir Rama Varma2,8,*, Aishwarya Patil3, Manjusha Nambiar4, Arathi S Nair5, Rhea Mathew6, PT Abhishek7
  • Total Page Count: 5
  • Page Number: 4871 to 4875

1Department of Orthodontics and Dentofacial Orthopedics, Sri Rajiv Gandhi College of Dental Sciences, Bangalore

2Clinical Assistant Professor, Department of Clinical Sciences, Ajman University, Ajman, UAE

3Department of Oral and Maxillofacial Pathology, S. Nijalingappa Institute of Dental Science and Research, Gulbarga

4Department of Periodontics, Sri Rajiv Gandhi College of Dental Sciences, Bangalore

5Department of Conservative Dentistry and Endodontics, Sri Rajiv Gandhi College of Dental Sciences, Bangalore

6Department of Conservative Dentistry and Endodontics, Sri Rajiv Gandhi College of Dental Sciences, Bangalore

7Department of Oral and Maxillofacial Surgery, Century International Institute of Dental Science and Research Center, Kasaragod

8Center of Medical and Bio-Allied Health Sciences Research, Ajman University, Ajman, UAE

*Corresponding Author E-mail: s.varma@ajman.ac.ae

Online published on 3 March, 2023.

Abstract

The world is undergoing its biggest health crisis named coronavirus disease, which is associated with increased proinflammatory cytokine storm, which ultimately leads to various medical complications including acute respiratory distress syndrome. The treatment protocol was always controversial due to the excessive use of corticosteroids in aggressive pneumonia and associated hyperinflammatory conditions.The excessive use, misuse, and rampant use of steroids may lead to various coinfection like mucormycosis which is referred to as black fungus that manifests within the skin and also affects the lungs and brain which may be more fatal. It is necessary to have early diagnosis and management to tackle the severity of post covid coinfection.

Keywords

Cytokine Storm, Corticosteroids, Mucormycosis, Pneumonia, SARS Covid 19