Research Journal of Pharmacy and Technology
SCOPUS
  • Year: 2022
  • Volume: 15
  • Issue: 11

Green synthesis of Zirconia nanoparticles based on ginger root extract: Optimization of reaction conditions, application in dentistry

Department of Biotechnology, School of Bio and Chemical Engineering, Sathyabama Institute of Science and Technology, Chennai - 600119

*Corresponding Author E-mail: thyagarajen@gmail.com

Online published on 3 March, 2023.

Abstract

Zirconia nano particles were synthesized from Zirconium oxychloride octahydrate using the extract of Zingiber officinale by Green synthesis. The synthesis was confirmed by the color change from pale yellow to pink. The synthesized nano particles were characterized by UV-visible spectrophotometer, Fourier Transform Infrared Spectroscopy (FT-IR), Scanning Electron Microscopy (SEM), X-ray Diffraction (XRD). The nanoparticles were found to be tetragonal with the XRD results. As an application in Dentistry, the activity of the zirconia nanoparticles were checked using well diffusion method with an oral bacterium, Streptococci mutans, and found the nano particles were inhibiting the growth of the bacterium.

Keywords

Zirconia, Response surface methodology, Characterization, Dental specimens, Nanoparticles