Research Journal of Pharmacy and Technology
SCOPUS
  • Year: 2022
  • Volume: 15
  • Issue: 2

Eight weeks consumption of high-fat diet promotes mesenteric fat deposition when compared to other rat diets

  • Author:
  • Khairil Azwan1, Resni Mona1, Jannathul Firdous1, Dina Keumala Sari3, Pamela Rosie David2, Noorzaid Muhamad1,*
  • Total Page Count: 4
  • Page Number: 571 to 574

1Cluster for Integrative Physiology and Molecular Medicine (CIPMM), Faculty of Medicine, Royal College of Medicine Perak, Universiti Kuala Lumpur, Jalan Greentown, 30450Ipoh, Perak, Malaysia

2Department of Anatomy, Faculty of Medicine, University of Malaya, 50603Kuala Lumpur, Malaysia

3Nutrition Department Faculty of Medicine, Universitas Sumatera Utara, Indonesia

*Corresponding Author E-mail: noorzaid@unikl.edu.my

Online published on 13 June, 2022.

Abstract

Metabolic syndrome is a grouping of several medical conditions plaguing the modern world today. Excessive visceral fat is strongly associated with abdominal obesity which is one of the characteristics of metabolic syndrome. In general, an unbalanced, rich diet plays an important role in the proliferation of adipocytes. Our aim is to observe which diet contributes to the deposition of visceral fat such as the mesenteric fat. For eight weeks, thirty-five Sprague Dawley rats were divided into five groups and were fed five different types of diets. The five diets are normal rat chow, high sugar, high starch, high protein and high fat rat (palm oil-based) feed formula. Besides the formularized rat feeds, the rats were given tap water ad libitum. The result showed high fat diet promotes mesenteric fat proliferation when compared to other rat feed formula. Present study showed that high-fat diet promotes mesenteric fat proliferation when compared to other diets.

Keywords

Diet, Enzymes, High-fat, Mesenteric fat, Palm oil