1Sechenov First Moscow State Medical University, 8 Trubetskaya St., Bldg. 2, Moscow, 119991, RussiaRussian Federation
2Federal Research Center of Nutrition, Biotechnology and Food Safety, 2/14 Ustyinsky pr., Moscow, 109240, RussiaRussian Federation
3Federal State Budgetary Institution “Scientific Centre for Expert Evaluation of Medicinal Products”, 8/2 Petrovsky Boulevard, Moscow, 127051, RussiaRussian Federation
4Botanical Garden of the University of Osnabrueck, Albrechtstr. 29, Osnabrueck, 490776Germany
*Corresponding Author E-mail: fmmsu@mail.ru
Online published on 13 June, 2022.
Phytochemical composition data of various parts of celery (Apium graveolens L.) and pharmacological activity there of are analyzed herein. Flavonoids, organic acids, hydroxycinnamic acids, ether oil terpenoids, tannins, vitamins and microelements are A. graveolens biologically active substances (BAS). Rich composition of BAS causes multiple both biological and pharmacological effects of herbal raw materials extracts mainly due to antioxidant activity. Furthermore, the extracts have neuroprotective, anti-inflammatory, hypolipidemic, antihypertensive and antibacterial effects. A. graveolens possesses wide spectrum of pharmacological activities and is a nontoxic plant; A. graveolens-based medicines will have high margin of safety. The results obtained provide opportunities for making herbal pharmaceutical celery-based substances and introduction there of into the academic medicine.
Celery, Apium graveolens, Extracts, Phytochemical Composition, Biologically Active Substances
