1Department of Biotechnology, MITS School of Biotechnology, Orissa - 751024, India
2S.K. Dash Centre of Excellence of Biosciences and Engineering and Technology, Indian Institute of Technology, Bhubaneswar - 752050, India
3Department of Biotechnology, School of Health and Allied Sciences, ARKA JAIN University, Jamshedpur - 831001, India
4School of Chemical Sciences, National Institute of Science Education and Research, Bhubaneswar - 752050, India
5District Public Health LaboratoryDistrict Head Quarters Hospital, Baripada - 757001, India
6Department of Biotechnology and Bioinformatics, Sambalpur UniversityJyotivihar - 768019, India
*Corresponding Author E-mail: bikashnou@gmail.com
Online Published on 08 June, 2022.
Nine actinobacteria were isolated from the mangrove soil of Bhitarkanika and screened for their bioactive metabolites and antimicrobial property. Out of the nine actinobacterial isolates, the bacterial isolateBAB-7 showed positive activity towards most of the enzymesscreened,i.e., Cellulase, phosphate solubilization, L-asparaginase, protease, and amylase. The actinobacterial isolate BAB-7 also exhibited antimicrobial activity against K. pneumoniae, V. alginolyticus, V. parahaemolyticus, P. aeruginosa,E. coli, S. typhimurium, and S. salivarius. Based on biochemical characterization, the actinobacterial isolate BAB-7 was identified as Steptomcessp. The secondary metabolites produced by the bacterial strain were analyzed through GC-mass spectroscopy and found to besimilar to the peaks of2-cyclohex-3-en-1-yl-2-oxoacetic acid derivative (ketomycin).
Antibiotics, Bioactive metabolites, Actinobacteria, Mangrove
