1M. S. College of PharmacyDevghar Taq-Wada District-PalgharMaharashtraIndia
2Adina Institute of Pharmaceutical Sciences, Sagar, Madhya Pradesh, India
3Institute of Pharmaceutical Research, GLA University, 17 Km Stone, NH-2, Mathura-Delhi Road, P.O. Chaumuhan, Mathura - 281406 (U.P.), India
*Corresponding Author E-mail: kamal0603@gmail.com
Online Published on 20 February, 2023.
A cost-effective and simple spectrophotometric technique is established for the quantification of Ofloxacin and Ketorolac tromethamine in bulk drug and eye drops. In the present case the method developed based on simultaneous equation method. The two wavelengths were selected that is 296 nm and 320 nm. The equation was designed and the absorption coefficients for both of the drugs at both the wavelength was calculated. The developed method was applied to formulations too. Analysis of results were statistically validated and by resurgence studies. For routine determination of Ofloxacin and Ketorolac tromethamine, the method was found to be suitable in bulk drug and in formulations. Therefore, the current work aims in developing an easy method for spectrophotometric determination of Ofloxacin and Ketorolac tromethamine in eye drop dose form.
Ofloxacin, Ketorolac tromethamine, Eye drop, Spectrophotometric, Fluoroquinolone, COX inhibitor
