Research Journal of Pharmacy and Technology
SCOPUS
  • Year: 2022
  • Volume: 15
  • Issue: 7

Spring snowflake (Leucojum vernum L.) and summer snowflake (L. aestivum L.): Chemical composition and uses in medicine

  • Author:
  • S. D. Kakhramanova1,2, M. N. Rodin1, D. O. Bokov1,*, N. D. Strelyaev1, A. I. Marakhova3, O. I. Perederyaev1, N. P. Balobanova1, A. A. Bondar1, I. I. Krasnyuk1, N. V. Friesen1,4, A. N. Luferov1
  • Total Page Count: 6
  • Page Number: 2945 to 2950

1Sechenov First Moscow State Medical University, 8, Trubetskaya St., bldg. 2, 119991, Moscow, RussiaRussian Federation

2Federal State Budgetary Institution “Scientific Centre for Expert Evaluation of Medicinal Products”, 8/2 Petrovsky Boulevard, Moscow, 127051, RussiaRussian Federation

3Peoples’ Friendship University of Russia (RUDN University), 6, Miklukho - Maklaya St., Moscow, 117198, Russia, Russian Federation

4Botanical Garden of the University of Osnabrück, Albrechtstr. 29, Osnabrück, 490776, Germany

*Corresponding Author E-mail: bokov_d_o@staff.sechenov.ru

Online published on 21 February, 2023.

Abstract

Snowflake genus (Leucojum L.) species currently have wide application as ornamental crops for the landscaping of gardens and parks. Previously, there were conducted several researches aimed at studying the composition of alkaloids as well as prospects for using these herbs as sources for medicines, in particular, containing galanthamine. This review shows systematical data on chemical composition (primarily, galanthamine and lycorine alkaloids) and medical application of two Snowflake species: spring snowflake (Leucojum vernum L.) and summer snowflake (Leucojum aestivum L.). There have also been considered issues concerning the standardization of medicinal plant raw material.

Keywords

Spring snowflake, Leucojum vernum, Summer snowflake, Leucojum aestivum, Amaryllidaceae alkaloids, Galanthamine, Lycorine, Lycorenin, Tazzetine