Research Journal of Pharmacy and Technology
SCOPUS
  • Year: 2022
  • Volume: 15
  • Issue: 8

Presence of virulence genes of Candida albicans isolated from women with remarks to Antifungal susceptibility

1Department of Microbiology, College of Medicine, University of Basrah, Iraq.

2Department of Microbiology and Parasitology, College of Veterinary Medicine, University of Basrah, Iraq.

*Corresponding Author E-mail: basil.abbas@uobasrah.edu.iq

Online Published on 23 February, 2023.

Abstract

Two hundred vaginal swabs were collected from clinic visiting women. The study revealed that 102 positive samples (51%) for the yeast isolation. The percentage was 51.11% in female below 30 years, while it was 50.76 % in women with age above 30 years. The highest levels of yeast isolation were found in relation with using of antibiotics, pregnant state and non-aborted women. By using disc diffusion method, several antifungal has the highest activity toward C. albicans such as fluconazole and clotrimazole while Iltrconazole and Amphotericin-B showed lower activity. The result of multiplex PCR showed that the most of the tested strains had ALS1, HWP and INT genes.

Keywords

Candida, Yeast, Human, Antibiotics, Virulence genes