Research Journal of Pharmacy and Technology
SCOPUS
  • Year: 2022
  • Volume: 15
  • Issue: 9

Variation of determination glycemic index of banana’s tuber of ambon (Musa paradisiaca var. sapientum), Kepok Banana (Musa paradisiaca var. formatypica) and Raja Banana (Musa paradisiaca var. raja) to Rat (Rattus norvegicus)

1Department of Pharmacy, Faculty of Medicine and Health Sciences, Universitas Islam Negeri Alauddin Makassar, Indonesia

2Faculty of Pharmacy, Universitas Muhammadiyah Kalimantan Timur, Samarinda, Kalimantan Timur, 75124, Indonesia

*Corresponding Author E-mail: syamsurisyakri@gmail.com

Online published on 27 February, 2023.

Abstract

The utilization of banana’s tuber was considering the nutritional content of banana’s tuber is quite high. This study aims to determine that glycemic index (GI) varieties of banana tuber given orally in rat. Banana tubers examined, among others, parasites banana ambon (Musa paradisiaca var. sapientum), kepok (Musa paradisiaca var. formatypica) and raja (Musa paradisiaca var. raja). Rats are grouped into 5 groups and each grup had 3 rats. The banana’s tuber is given in the form of flour suspended into 0,1% NaCMC with a dose of 2,5g/kgBW, a positive control of glucose oral dose 2,5g/kgBW. Blood sampling of test animals at hour 0 (before administration of test or control compounds); 0,5;1 and 2 hours after administration of the test compounds. The blood serum is then determined glucose level using glucometer. The data in the blood glucose leve; of the test versus time animal were analyzed into Area Under Curve (AUC) glucose versus AUC (0-2 hours). The calculation of GI is done by comparing AUC (0-2 hours) of test compound to AUC (0-2 hours) glucose. The results showed that the three varieties of banana tuber had low GI values, were Ambon’s banana’s tuber had a glycemic index amount 32,5; Kepok’s banana tuber had GI amount 25,5 and Raja’s banana tuber had GI amount 45,6.

Keywords

Glycemic Index, Flour banana’s tuber, Blood glucose, White mice, AUC